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C2HF3O2/c1-25(2)5-3-6-26(7-4-11(20)19(30)31)8-12-14(28)15(29)18(32-12)27-10-24-13-16(21)22-9-23-17(13)27
Cinaciguat (free base) is an experimental drug for the treatment of acute decompensated heart failure
Smiles: CC(=O)[C@@]1(O)CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
GluK2a (15-fold)
4 µM) in stress-cultured MEF cells but does not block IRE1α autophosphorylation
Glutaminase-IN-1 Size:Contact [email protected] for quotation C2HF3O2/c1-25(2)5-3-6-26(7-4-11(20)19(30)31)8-12-14(28)15(29)18(32-12)27-10-24-13-16(21)22-9-23-17(13)27Glutaminase IN 1 (CB839 derivative), a CB839 derivative, is an allosteric inhibitor of 1,3,4 selenadiazole containing kidney type glutaminase (KGA), with an IC50 of 1 nM. Glutaminase IN 1 (CB839 derivative) shows improved cellular uptake and antitumor activity. Product information CAS Number: 2247127 79 1 Molecular Weight: 618. 47 Formula: C26H24F3N7O3Se Chemical Name: 2 (pyridin 2 yl) N {5 [4 (6 {2 [3 (trifluoromethoxy)phenyl]acetamido}pyridazin 3
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