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DG172 dihydrochloride is a selective PPARβ/δ antagonist
Nutlin-3a effectively depletes the S-phase compartment to 0
although it is no longer used for the latter due to bacterial resistance
Smiles: COC1=CC(Br)=C(C=C1OC)S(=O)(=O)NC1=CC(O[C@H]2CN(C)CC2)=C(Cl)C=C1
InChi: InChI=1S/C24H25ClFN5O2/c1-33-22-14-20-17(24(28-15-27-20)29-16-7-8-19(26)18(25)12-16)13-21(22)30-23(32)6-5-11-31-9-3-2-4-10-31/h5-8
2', 3', 5'-triacetyl-5-Azacytidine Size:Contact [email protected] for quotation DG172 dihydrochloride is a selective2',3',5' triacetyl 5 Azacytidine (TAC) is the lead prodrug form of 5 azacytidine which may be rapidly absorbed after oral administration . 5 Azacytidine is an inhibitor of DNA methyltransferase . The DNA methyltransferase belongs to a family of enzymes involved in catalyzing the transfer of a methyl group to DNA. DNA methylation has been implicated in regulating gene expression in normal and malignant cells . In vivo: In CD 1 mice, oral administration
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