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SKP2-C25 exhibits potent antitumor activities in multiple animal models and cooperates with chemotherapeutic agents to reduce cancer cell survival
Formula: C28H40BrN7O4
N106 directly activates the SUMO-activating enzyme
Smurf2 and WWP1 with IC50 6
CB-5083 appears to exhibit greater potency over current proteasome inhibitors that further validate targeting p97 and protein homeostasis in the treatment of cancer
Py-ds-But-OSu - CAS# 115088-06-7 Library of Histone Demethylase SKP2-C25 exhibits potent antitumor activitiesDemethylzeylasteral (T 96), CAS No. 115088 06 7, the active component isolated from Tripterygium wilfordii Hook F., inhibits UDP glucuronosyltransferase (UGT) isoforms UGT1A6 and UGT2B7 with immunosuppressive effects. Product information CAS Number: 115088 06 7 Molecular Weight: 326. 39 Formula: C13H14N2O4S2 Synonym: SPDB Chemical Name: (2, 5 dioxopyrrolidin 1 yl) 4 (pyridin 2 yldisulfanyl)butanoate Smiles: O=C(CCCSSC1=CC=CC=N1)ON1C(=O)CCC1=O
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